I also did human growth on 2 cycles and didn't help a bit. I just had my first IVF and it was unsuccesful. How it works: It's a two cycle process. I hope a tweak of the protocol will help or maybe it was just an off cycle for me. He is starting me on a peculiar Omnitrope protocol as well:- he wants me mixing two vials of omnitrope in 10 mL of water and inject myself with 1 mL daily until egg retrievaland to keep refilling the Rx until retrieval. I'm feeling really low right now and can't shake the thought of trying IVF for the first time to attempt a bio child. Some reproductive endocrinologists will change the treatment strategy based on the number of follicles available at the start of the cycle. One well regarded study determined that amongst most IVF patients, those taking over 150 IUs per day of gonadotropin had higher rates of success than those who took less. Best of luck to you. Within both, doctors can prescribe as much gonadotropin as theyd like. Did acupuncture, Chinese herbs, modified diet, re-tested and FSH was 7 / Estradiol 47/ AMH .4 You can be assured it is a good protocol. I understand the idea for the patch is to help time the growth of follicles vs. increase the number? Was wondering since your AMH was good and FSH, why did they recommend the Estrogen priming protocol for you? Today, were seeing more well-respected doctors choosing to compliment lower dose of gonadotropin with clomid or letrozole in this group. It's hard for me to say definitively because I haven't had wtf yet. The dose of gonadotropin is typically measured in International Units Per Day and ranges from 0 - 900 with most IVF patients receiving 250 - 450 IUs per day. I started the estrace (I am doing pills) 2mg 2x/day 7 days after a positive OPK, and then continuing throughout stims. IVF#4 November 2009 - one embryo survived to day 3 transfer - BFN We're banking this cycle and testing them with the biopsies from the next. 13 days stim. Associate Director, REI An FSH drop-down protocol is used to What Research Says About Stress as a Cause of Infertility, 7 Ways to Help Overcome Grief after Pregnancy Loss, Sometimes Getting Pregnant is Not the Issue, From Eggs to Blastocysts: Understanding IVF Attrition, Let's Stop Arguing About Whether or Not Stress Causes Infertility, Gift Ideas For Someone Experiencing Infertility, FertilitySmarts Explains Estrogen Priming. I also did ganirelix during this time. This is not recommended for shared computers. I asked my local RE about it, but she wasn't familiar enough with it to try. By clicking sign up, you agree to receive emails from FertilitySmarts and agree to our Terms of Use & Privacy Policy. They said that they look at FSH less now as they find it too unreliable. I then switched clinics. Surprise spontaneous just 7 months postpartum while still breastfeeding!!! By: Kelly Park I just had an appointment with an RE who told me that because of my high FSH levels there is low probability of me being able to get pregnant, but he also said that he could not do IVF or I could not take any fertility drugs because it would only be mimicking what my body is already trying to do and that is not even working. BFP October 22!!!! I started my estrace this morning and feel a little icky so far. I'm 40, doing IVFdue to age and a mc at 10 weeks due to Trisomy18. We're also doing PGS. E2 level 96.4. This drug takes longer to work and needs to be taken before stimulation starts. I was on BCP for 15 years and when I went off them I never got my period. Why so many days of esterace( 15-16 days before starting/adding promethium for 10 days) then the stim cycle, 3. I credit the advice I received on this forum both from members and from experts, my infertility doctor and my push for the estrogen priming protocol for the family that I have today. This helps to improve the outcome of the IVF cycle in patients who respond poorly to traditional IVF protocols. Spandorfer said it would not suppress me to much not sure about this, need to speak with him further. So I think I was on estrogen for about a couple weeks then started stimming (antagonist protocol). Advertising Policy - I had 5 follicles but only one matured so I was converted to IUI which failed. In my case, antral follicle count is very poor, but RE decides to proceed. Get Ready for a New Season of Gardening -Choose from Tomatoes, Peaches, Corn, Zinnias & More! To bridge that gap, doctors prescribe drugs that woman take at the start of a cycle to instigate growth of ovarian follicles that contain eggs. Fx! This drug acts directly on the follicles to start this process and causes (italics) OHSS. Around 50-60% of couples find success with IUI after 5 cycles, which is about a 10-20% success rate per cycle. Very helpful! Copyright 2023 They said they would put me in the 21 day long protocol. After my period started, my doctor kept me on the patches for five more days. Yes, I did antagonist for IVF 1, 2 and 3. This drug prompts the brain to release LH, the signal for ovulation, and is effective in helping to avoid OHSS. Beta 2093 Best of luck x Reply Quote IVF #2, we did estrogen priming, Follistim, Menopur, Tev Tropin (human growth hormone), Cetrotide. Ganirelix is contraindicated in pregnancy. Comparing protocol A and B, there were no significant difference between embryologic data, however there were slight . I was long Lupron and that one was cancelled because my precious RE only saw very few follies. Thanks so much! Estrogen Priming Protocol - Infertility Inspire Finding a Resolution for Infertility IUI / IVF and high-tech procedures Finding a Resolution for Infertility Infertility Support Community in Partnership with RESOLVE Join Inspire Create a Post Estrogen Priming Protocol blossom34 (Inactive) Sep 23, 2010 5:34 AM Experience with Estrogen Priming Protocol? This time I have to use 450iu of Gonal/follistem and 150iu of Menopur each day and I pay out of, I recently attempted my first IVF. SG usually sticks to their protocol for the first round, then if it fails, they'll start customizing. Most of the encouraging studies have been in poor responders, but because the trials were so small, most never met statistical significance. Back to home page. This educational content is not medical or diagnostic advice. Our usual regimen is similar to those proposed below: hysteroscopy, prolonged estrogen priming, Estring for local effects, baby aspirin, vaginal phosphodiesterease inhibitors, pentoxifylline, acupuncture, etc., with admittedly little data to support any of our treatment strategies. Some people prefer the term Diminished Ovarian Reserve or Low Egg Reserve for patients who meet this criteria, as the ovarian response to medications for this group is not always necessarily poor, but rather is simply expected to be lower at their given baseline. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. OHSS can be both painful and dangerous. FertilitySmarts Inc. - Estrogen priming also allows the patient and clinicians to schedule the ovarian stimulation cycle and the timing of egg retrieval. This community is sponsored by RESOLVE: The National Infertility Association, an Inspire trusted partner. You currently have javascript disabled. Whats important to stress here is that just because some low dose approaches drive comparable rates of success to conventional approaches, that doesnt mean all low-or-no dose approaches are effective. An analysis that combined six extremely small studies (that in aggregate only included about 160 patients) show gains in live birth rates, as you can see below. Once multiple follicles start growing, its important that they are not ovulated before they can be collected in an egg retrieval. But I will be asking the best hardcore questions I can come up with about EPP. Thanks for well wishes. After it happens, I keep receiving bills in the mail. This was my worst cycle ever only yielding 2 retrieved follicles that did not fertilize. BabyCenter may earn a commission from shopping links. After 5 days of estrogen priming Follitropin alpha (Gonal F, 600 IU/day, s.c.) is started. Slightly higher doses of Follistim and Menopur to try to get a few more eggs. Had three chromosomal miscarriages last year, moved on to IVF with intention of genetic testing but had to cancel cycle a few days in, E2 never got above 36 while on max dose of 300 Gonol f and 300 Menopur. I am praying this makes a huge difference. Here's what you need to know about the project. Those 2 were my worst cycles. We did an antagonist protocol with gonal f, menopur and ganirelix last time and only ended up with 2 embryos on day 3 if that helps. Check out this video to learn more about the. You may wonder how thats possible. Im very new to this, have never done an IVF cycle but was hoping to start soon. You are posting as a Guest without being logged in. November 8 - we're having twins:) Wow!!! Often two other types of drugs are needed to accompany gonadotropin: those that block eggs from maturing and being ovulated before they can be retrieved, and those that help trigger the eggs to mature so they can be retrieved. How many follicles were you usually starting with? Lupton trigger. i read everywhere it's for "poor responders". I hope you like the protocol. RE put me on Estrogen priming protocol, and I am on Lupron and Cetrotide as well.On Friday, (cycle day 6) the newer nurse thought she saw 11 follicles.. ranging from 5mm to 9mm.. now, Cycle day 9, the other nurse, who has been there forever, saw only 5 and she had a hard time locating my other ovary. This will be my first IVF round and I w, Hi All, Another distinctive feature between the two protocols is that the Long Agonist protocol calls for a longer stretch of drugs to block ovulation. Its effective, but expensive, and raises the risk of OHSS. Im on this for 21 days starting on cycle day 1. As a result, the Antagonist strategy is generally preferred for women at especially high risk of developing OHSS, namely women with PCOS, younger women, women with high AMH or AFCs, African American women, and those who produced a high number of eggs in a recent cycle. Is a micro-dose lupron protocol considered a low-dose protocol? ET oct 2nd - 2 embryos transferred It's easiest to create a Word docume, Prevent & Address Internal White Tissue in Tomatoes | How to Maximize Potassium Uptake and Reduce Fungal Diseases, Tomatoes are a popular and nutritious vegetable that can be grown in gardens around the world. ) Wow!!!!!!!!!!!!!!... Decides to proceed well-respected doctors choosing to compliment lower dose of gonadotropin with or. I asked my local RE about it, but expensive, and is in... Icky so far B, there were slight follicles vs. increase the number trusted partner Privacy.... Hope a tweak of the IVF cycle in patients who respond poorly to traditional IVF protocols tweak of the will. 5 follicles but only one matured so I think I was converted to IUI which failed this and... Poorly to traditional IVF protocols the follicles to start this process and causes ( italics OHSS... Know about the FertilitySmarts and agree to our Terms of Use & Privacy Policy to. Be taken before stimulation starts sticks to their protocol for the first round, then if it fails they... As they find it too unreliable mc at 10 weeks due to Trisomy18 a micro-dose Lupron protocol considered a protocol! Me on the patches for five more days sticks to their protocol you.!!!!!!!!!!!!!!!!!... Try to get a few more eggs the ovarian stimulation cycle and the timing of egg.. Up with about EPP National Infertility Association, an Inspire trusted partner the. Was wondering since your AMH was good and FSH, why did they recommend the Estrogen priming also allows patient! 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