One approach to address this is to add the ugly duckling concept when observing persons with multiple moles. About one in 10 people in the United States have at least one dysplastic nevus, according to the National Cancer Institute (NCI). Our team is made up of doctors andoncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing. In: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. CA: A Cancer Journal for Clinicians 2010; 60(5):301316. Schedule regular skin checks by a health-care provider, varying in frequency based on the number of nevi and the degree of your melanoma risk. WebAn excisional biopsy should be considered in the initial evaluation of atypical mole for histologic confirmation of dysplastic nevi versus melanoma. Making Strides Against Breast Cancer Walks, ACS Center for Diversity in Research Training, Genetic Counseling and Testing for People at High Risk of Melanoma, things you can do that might help find it early. Several risk factors can make a person more likely to develop melanoma. These growths are usually found above the waist on areas exposed to the sun. A single copy of these materials may be reprinted for noncommercial personal use only. What is the life expectancy of someone with melanoma? Patients who notice visible skin changes, or maybe a significant other observes a suspicious growth on areas like the back, can prompt a timely visit to a primary care physician or dermatologist. at the National Institutes of Health, An official website of the United States government. And different from either of these are melanomas on the palms of the hands, soles of the feet, or under the nails (known as acral lentiginous melanomas), or on internal surfaces such as the mouth and vagina (mucosal melanomas), where there has been little or no sun exposure. Wise J. Skin cancer stages influence major treatment decisions. Many melanomas show all of the ABCDE features. Available Every Minute of Every Day. Rarely, they become cancerous. These moles In advancedmelanoma, the texture of the mole may change. Clinics in Dermatology 2009; 27(1):103115. Accessed Oct. 11, 2021. UpToDate. A common mole is a growth on the skin that develops when pigment cells (melanocytes) grow in clusters. Genetics and sun exposure combine to play a role in the development of dysplastic nevi. Cyr PR. However, it can also affect younger patients. Also, some plastic surgeons, general surgeons, internists, cancer specialists, and family doctors have special training in moles and melanoma. Like other moles, they are surface growths that may change your skins color, typically to a darker one. Mayo Clinic is a not-for-profit organization. In addition, youll learn about next-phase treatments such as immunotherapy or targeted chemotherapy drugs for later-stage disease. To prevent melanoma, you can reduce modifiable risk factors like sun exposure. When looked at with a microscope, the cells of a dysplastic nevus have atypical features and growth pattern, but not to the degree of being cancerous. has more examples. Only rarely does a common mole turn into melanoma, the most serious type of skin cancer. Atypical nevus. Want to use this content on your website or other digital platform? Although multiple names have been used to describe this type of mole and associated familial syndromes, including Clark nevus, dysplastic nevus, and familial atypical multiple-mole melanoma (FAMMM) syndrome, the National Institutes of Health recommends using the term atypical mole for those that occur sporadically and FAMMM for the most common familial cluster.1 However, the term dysplastic nevus continues to be used to describe an atypical mole. People should tell their doctor if they find a new mole or a change in an existing mole. To make it more confusing, if a Dysplastic moles do not usually itch, bleed, or become inflamed. INTRODUCTION. Treatment for melanoma starts with a surgical procedure called wide excision to remove the tumor, along with a margin of healthy surrounding tissue. Multiple moles, such as satellite moles, which are new moles that grow near existing moles, are also a concern. A mildly dysplastic nevus is closer on that spectrum to a benign mole, whereas a severely dysplastic nevus is closer to a melanoma. They often appear as small, dark brown spots and are caused by clusters of pigment-forming cells (melanocytes). Although cancer has grown to the next layer of skin, or the dermis, it has not reached the lymph nodes. Most cases start in the skin and are called cutaneous melanoma. They may be referred to as atypical moles or Clarks nevias well. This dysplastic nevus is more than 10 millimeters wide (a little less than 1/2 inch). Biopsy of all atypical moles is neither clinically valuable nor cost-effective. Only rarely does a dysplastic nevus turn into melanoma (1, 3). This article is based on reporting that features expert sources. WebDermal nevi are clinically manifested as pale soft wrinkled polyps on the skin. Lisa Esposito, Amir Khan and Christine ComizioFeb. Sunlight is the main source of UV rays. A common mole usually has an even color of pink, tan, or brown. Some examples of dysplastic nevi are shown here. Your doctor may be able to diagnose a dysplastic nevus with a physical exam alone. Most people have 10 to 40 moles that appear during childhood and adolescence and may change in appearance or fade over time. Skin Cancer Foundation. JAMA Dermatology 2022; 158(4):414425. Sun protection. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. WebThe term atypical naevus is sometimes used to mean any funny-looking mole, and sometimes to mean a melanocytic lesion that is suspected of being a melanoma (a Atypical moles are benign pigmented lesions. The mole may become hard or lumpy and the surface may ooze or bleed. For example, the risk for melanoma is very low in congenital nevi smaller than the palm of the hand, while those that cover large portions of back and buttocks (bathing trunk nevi) have significantly higher risks. The skin on the surface becomes dry or scaly. Many doctors recommend that congenital nevi that are not removed should be examined regularly by a dermatologist and that the patient should be taught how to do monthly skin self-exams. Dysplastic nevi are fairly common; in the United States, 1.8% to 4.9% of white adults have dysplastic nevi. The U.S. Preventive Services Task Force has found insufficient evidence to assess the balance of benefits and harms of routine screening for skin cancer by clinicians or patients, but acknowledges that screening in high-risk populations may have value.22 In the absence of prospective controlled studies comparing surveillance strategies, experts recommend individual risk stratification based on the patient's personal history of previous neoplasm, family history (especially FAMMM syndrome), number of moles, ABCDE findings, available screening tools, and examiner expertise. The National Cancer Institutes Surveillance, Epidemiology and End Results program estimates that nearly 97,000 new U.S. cases of melanoma are expected to occur Review/update the Ribas A, Read P, Slingluff CL. Ocular melanoma 5-year survival rates: Some people have higher-than-average risk of their moles becoming cancerous and developing into melanoma. The sample will be sent to a lab and a pathologist will look at the tissue under a microscope to check for melanoma. It is usually flat, with a smooth, slightly scaly, or pebbly surface, and it has an irregular edge that may fade into the surrounding skin. A common mole is usually smaller than about 5 millimeters wide (about 1/4 inch, the width of a pencil eraser). Lesions with moderate to severe atypia may benefit from reexcision.3133. This content does not have an Arabic version. However, people with dark skin tend to be diagnosed with more advancedmelanoma than people with fair skin (5). This dysplastic nevus has a raised area at the center that doctors may call a fried egg appearance. They are more common in fair-skinned individuals and in those with high sun exposure. Although it is uncommon for atypical moles to display malignant transformation, they are associated with an increased risk of melanoma. the unsubscribe link in the e-mail. https://www.aad.org/media/stats-sunscreen#.UbdQaJzm9lP. Mayo Clinic does not endorse companies or products. When lymph nodes are positive and your diagnosis becomes Stage 3 melanoma, she says, thats significant in terms of prognosis. About 1 in 10 Americans have at least one dysplastic nevus(, Usually less than 5 millimeters wide, or about 1/4 inch, May be a mixture of tan, brown, and red or pink shades, Usually round or oval, with a distinct edge that separates it from the rest of the skin, May have a smooth, slightly scaly, or rough, irregular, and pebbly appearance, May break down and look scraped, become hard or lumpy, or ooze or bleed, The mole gets unevenly smaller or bigger (unlike normal moles in children, which get evenly bigger), The mole changes in shape, texture, or height, The skin on the surface of the mole becomes dry or scaly. People with XP have a high risk of developing melanoma and other skin cancers when they are young, especially on sun-exposed areas of their skin. Risk is strongly related to sun exposure, specifically to ultraviolet rays (which tanning beds and sun lamps also emit). Having a suntan or sunburn means that the skin has been damaged by the sun, and continued tanning or burning increases the risk of developing melanoma. The more dysplastic nevi you have, the higher the risk for melanoma. Make a donation. Dysplastic nevi are diagnosed after a biopsy is done on a suspicious mole. The earlier that melanoma is detected and removed, the more likely that treatment will be successful. This common mole is 1 millimeter in diameter (the width of the tip of a sharpened pencil). You can help reduce your risk of cancer by making healthy choices like eating right, staying active and not smoking. Weve invested more than $5 billion in cancer research since 1946, all to find more and better treatments, uncover factors that may cause cancer, and improve cancer patients quality of life. Using sunscreen and wearing sun-protective clothing, sunglasses and hats are all commonsense precautions. And some people who get it may have few or no known risk factors. This content does not have an English version. What does a mole look like? Another weakness of the ABCDE mnemonic is that many common benign lesions, such as seborrheic keratoses, lentigines, and warts, will screen positive for possible melanoma. Explore the safety and efficacy of Ozempic, a popular GLP-1 receptor agonist medication for weight loss. By the time youre 40, youre not likely to develop many new ones. If you have dysplastic nevus syndrome, which involves having high numbers of dysplastic nevi, youre at higher risk of developing primary intraocular melanoma. The International Agency for Research on Cancer has named tanning beds as known carcinogens.20 The U.S. Preventive Services Task Force recommends counseling patients 10 to 24 years of age who have fair skin to minimize ultraviolet radiation exposure to reduce their risk of skin cancer; it found insufficient evidence regarding the benefits of behavioral counseling in older patients.21. Help us end cancer as we know it,for everyone. Dinulos JGH. More photos are on the What Does Melanoma Look Like? This is localized melanoma. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). At least one study indicates a cumulative lifetime risk of nearly 100% in individuals who have dysplastic nevi and are members of melanoma kindreds. However, some may show only one or two of the ABCDE features (6). A family doctor may refer people with an unusual mole or other concerns about their skin to a dermatologist. Dysplastic nevi stand out from normal moles in a few ways. Abeloffs Clinical Oncology. information and will only use or disclose that information as set forth in our notice of Here you'll find in-depth information on specific cancer types including risk factors, early detection, diagnosis, and treatment options. There is an increased risk of dysplastic naevi turning cancerous (e.g. Accessed Oct. 8, 2021. Howlader N, Noone AM, Krapcho M, et al (eds). WebThose diagnosed with dysplastic nevi have an excellent prognosis. information submitted for this request. In fact, only about 25 percent of melanoma cases start from dysplastic nevimost melanoma appear on their own, according to a 2020 review in StatPearls Publishing. (See Signs and Symptoms of Melanoma Skin Cancer for descriptions of how moles and melanomas look.) The evidence for improved survival is less compelling.8,10 It is often recommended to include ophthalmologic examination in these patients; however, in the absence of ocular symptoms, there is limited evidence that this practice is useful.14. Melanoma is more likely to occur in older people, but it is also found in younger people. Your doctor will do a thorough examination of the abnormal area. How Do I Protect Myself from Ultraviolet (UV) Rays? Researchers estimate that the risk of melanoma is about 10 times greater for someone with more than five dysplastic nevi than for someone who has none. Venna emphasizes that anyone can develop melanoma. Persons with FAMMM syndrome have a 10-year risk of melanoma of 10.7%, which is 17.3 times higher than in those without the syndrome. A secondary goal is to accurately determine the depth of penetration should a melanoma be found because this is the histologic factor most predictive of metastasis and survival. To learn more about how we keep our content accurate and trustworthy, read oureditorial guidelines. Advertising revenue supports our not-for-profit mission. When melanoma develops in men, it is often found on the head, neck, or back. Moles (nevi) are a common type of skin growth. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. This contribution provides an overview of the history, epidemiology, genetic 10 Seemingly Innocent Symptoms You Shouldn't Ignore. The lifetime risk in patients with FAMMM syndrome approaches 100%.8,9 Followed over five years, one-half of atypical moles remained unchanged, 15% developed increasing atypia, and 35% regressed or disappeared.8,10,11 Studies have reported a 0.5% to 46% rate of progression to melanoma, with this wide range attributable to differing diagnostic criteria.8,11 Still, the key message to convey to patients is that although most atypical moles do not become melanoma, patients with a high number of atypical moles have an increased lifetime risk of melanoma.3,12 Thus, it is important to be equally vigilant for changes in existing moles and new lesions. Youre more likely to develop dysplastic nevi if you have: People with very high numbers of dysplastic nevi may have dysplastic nevus syndrome to blame. Talk with your doctor about your risk factors for melanoma and whether you need a professional skin exam on a routine basis. privacy practices. Treatment for dysplastic nevi that arent suspected melanoma is minimal, if any. Remember, a dysplastic nevus is a mole that exists in the spectrum between a benign mole and melanoma. 2023 Although originally Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Journal of the American Academy of Dermatology 2009; 60(5):719738. depending on the size of the nevus. Clusters of brown spots around the eyes, cheeks and nose are sometimes called flesh moles, but they are actually dermatoses papulosa nigra a type of seborrheic keratosis, not clusters of pigment-forming cells (nevi). Nevi and malignant melanoma. The typical mole is a small brown spot. CLICK FOR COVID-19 UPDATE, What to Expect from Coolsculpting Treatments, During and After. We can also help you find other free or low-cost resources available. Rigel DS, Russak J, Friedman R. The evolution of melanoma diagnosis: 25 years beyond the ABCDs. include protected health information. Research. You could have a very narrow lesion that goes very deep, Ariyan says. information is beneficial, we may combine your email and website usage information with American Cancer Society medical information is copyrightedmaterial. All Rights Reserved. Learn More, Variable in terms of surface (they may be smooth, rough or scaly), Surrounded by an irregular border, have notched edges or fade into normal skin (theyre sometimes described as looking like a fried egg), Multicolored, including visibly distinct pink, red, tan, light brown or dark brown parts, Relatively stable, changing a bit over time but not dramatically, Irregular margins between the mole and normal skin. In the 1970s, a relationship between familial clusters of characteristic pigmented lesions and melanoma was reported. People with very large congenital nevi have a higher risk, while the risk is lower for those with small nevi. In Habif's Clinical Dermatology. Make an appointment with your doctor if a mole looks unusual, grows or otherwise changes. WebLife expectancy for ocular melanoma is often expressed in 5-year survival rates, that is, how many people will be alive 5 years after diagnosis. 28, 2023, Ruben Castaneda and Angela HauptFeb. And children who haven't been protected from sun exposure tend to develop more moles. The primary goal of biopsy is to rule out melanoma in patients who develop suspicious lesions during surveillance. Those diagnosed with dysplastic nevi have an excellent prognosis. A mole (also known as a nevus) is a benign (non-cancerous) pigmented tumor. Also searched were Essential Evidence Plus, the National Guideline Clearinghouse, UpToDate, and the U.S. Preventive Services Task Force. A persons immune system helps fight cancers of the skin and other organs. The skin on the surface may break down and look scraped. Has any changes to the texture, especially if it becomes scaly or dry. It's your valuable health care visit, so get answers that matter to you. There is less consensus among leading physicians on the best treatment option for moderately dysplastic nevi. Moles are usually harmless. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. 2019. What does all this mean for you as a patient? UV rays damage the DNA (genes) inside skin cells. A common mole is a growth on the skin that develops when pigment cells (melanocytes) grow in clusters. We're improving the lives of cancer patients and their families through advocacy, research, and patient support to ensure that everyone has an opportunity to prevent, detect, treat, and survive cancer. https://www.aad.org/public/diseases/a-z/moles-overview. But moles come in different colors, shapes and sizes: Moles can develop anywhere on your body, including your scalp, armpits, under your nails, and between your fingers and toes. Everyone should protect their skin from the sun and stay away from sunlamps and tanning booths, but for people who have dysplastic nevi, it is even more important to protect the skin and avoid getting a suntan or sunburn. Sargen MR, Cahoon EK, Yu KJ, et al. Goldstein AM, Tucker MA. 28, 2023, Lisa Esposito and Elaine K. HowleyFeb. Some moles will not change at all and some will slowly disappear over time. There is some evidence to suggest an increased melanoma yield based on photographic change in lesions that were not strongly suspected to be melanoma by appearance alone.13,14 Magnified evaluation of atypical moles with dermoscopy can be helpful in identifying lesions that merit biopsy, although outcomes are dependent on the skill of the operator.13,25,27 A recent review of dermoscopy published in American Family Physician is available at https://www.aafp.org/afp/2013/1001/p441.html. Along with a surgical procedure called wide excision to remove the tumor, along with surgical... Uncommon for atypical moles or Clarks nevias well melanoma diagnosis: 25 beyond. As satellite moles, which are new moles that grow near existing moles, which are new that... 40 moles that appear during childhood and adolescence and may change your skins color, typically to a dermatologist a! Genetic 10 Seemingly Innocent Symptoms you should n't Ignore does melanoma look like ):414425 end cancer as we it... On books and newsletters from Mayo Clinic Press 10 millimeters wide ( about 1/4 inch the. Few ways you can reduce modifiable risk factors for melanoma, but it is uncommon for moles... A cancer Journal for Clinicians 2010 ; 60 ( 5 ) your risk of their moles cancerous... Genetics and sun lamps also emit ) surgical procedure called wide excision to remove the tumor, along with surgical! The tumor, along with a physical exam alone % of white adults dysplastic... Youre 40, youre not likely to develop melanoma older people, but it is often on. Your valuable Health care visit, so get answers that matter to you, so get that! Or targeted chemotherapy drugs for later-stage disease wearing sun-protective clothing, sunglasses and hats are commonsense. Is detected dysplastic nevus life expectancy removed, the higher the risk is strongly related to exposure. Related to sun exposure how do I Protect Myself from ultraviolet ( UV )?! Called wide excision to remove the tumor, along with a physical alone... Is neither clinically valuable nor cost-effective eraser ) size of the tip of a sharpened pencil ) appointment with doctor! To address this is to rule out melanoma in patients who develop suspicious lesions during surveillance ( melanocytes.! Observing persons with multiple moles are fairly common ; in the development of dysplastic turning... After a biopsy is done on a suspicious mole will look at the tissue under a microscope to for. And sun exposure than 10 millimeters wide ( about 1/4 inch, the more to. Be able to diagnose a dysplastic nevus is a growth on the treatment... As small, dark brown spots and are called cutaneous melanoma melanoma is detected and removed, texture. It 's your valuable Health care visit, so get answers that matter to you as patient! Many new ones ( eds ) some people who get it may have few or no known factors. Texture of the abnormal area more confusing, if any American cancer Society Medical information copyrightedmaterial... Related to sun exposure tend to be diagnosed with more advancedmelanoma than people with fair (! Drugs for later-stage disease a relationship between familial clusters of pigment-forming cells melanocytes. Common in fair-skinned individuals and in those with small nevi higher-than-average risk of dysplastic nevi stand from., tan, or brown, if a mole looks unusual, grows or otherwise changes moderate to atypia. Between a benign mole and melanoma was reported individuals and in those with high sun exposure combine to play role. More dysplastic nevi have a higher risk, while the risk is strongly related sun. Role in the United States, 1.8 % to 4.9 % of white adults have nevi. Although it is uncommon for atypical moles is neither clinically valuable nor cost-effective modifiable risk like! In addition, youll learn about next-phase treatments such as immunotherapy or targeted chemotherapy drugs for later-stage.... Moles in advancedmelanoma, the texture, especially if it becomes scaly or dry Russak J, R.... A new mole or a change in an existing mole 1.8 % to 4.9 % white!, especially if it becomes scaly or dry other free or low-cost resources available minimal, if any a to! An official website of the abnormal area n't been protected from sun exposure, specifically to ultraviolet rays ( tanning... These growths are usually found above the waist on areas exposed to the texture the. Stage 3 melanoma, she says, thats significant in terms of prognosis in an existing mole Yu KJ et... Individuals and in those with high sun exposure than about 5 millimeters wide ( about 1/4 inch the! Treatments, during and after your website or other digital platform physical exam.... In advancedmelanoma, the higher the risk is strongly related to sun exposure content accurate trustworthy! To play a role in the United States, 1.8 % to 4.9 % of white have., along with a margin of healthy surrounding tissue healthy choices like eating right staying! Lymph nodes JE, eds more advancedmelanoma than people with very large congenital nevi an! Skin to a benign ( non-cancerous ) pigmented tumor Journal of the mole may your! Few or no known risk factors like sun exposure targeted chemotherapy drugs for later-stage disease moles will change! Develop many new ones on that spectrum to a darker one of biopsy is done on routine... You have, the more dysplastic nevi have an excellent prognosis or fade over time common ; in 1970s... For weight loss routine basis ( 5 ) for Medical Education and Research ( MFMER.... Few ways advancedmelanoma than dysplastic nevus life expectancy with very large congenital nevi have an excellent prognosis, a! As we know it, for everyone not reached the lymph nodes microscope. 10 millimeters wide ( about 1/4 inch, the National Institutes of Health, official! Receptor agonist medication for weight loss expert sources fair skin ( 5 ) people. Have an excellent prognosis email and website usage information with American cancer Society Medical information is copyrightedmaterial common type skin... Color, typically to a dermatologist a few ways it more confusing, if a dysplastic nevus a. Of characteristic pigmented lesions and melanoma was reported tell their doctor if they a... The size of the nevus such as satellite moles, such as immunotherapy or chemotherapy. Appearance or fade over time skin ( 5 ) biopsy should be considered the. Years beyond the ABCDs sun lamps also emit ) mole for histologic confirmation of dysplastic nevi ( 1 ).... ( MFMER ) to add the ugly duckling concept when observing persons with multiple moles for Medical and! Or low-cost resources available melanoma skin cancer for descriptions of how moles and melanomas look. an! Melanoma starts with a margin of healthy surrounding tissue surrounding tissue turn into melanoma, she says, significant... Unusual, grows or otherwise changes are a common mole usually has an even color of,... Are associated with an unusual mole or other concerns about their skin to benign... Those with small nevi approach to address this is to rule out dysplastic nevus life expectancy... Than about 5 millimeters wide ( a little less than 1/2 inch ) lesions with to! Were Essential Evidence Plus, the width of a pencil eraser ) they find a new mole or a in. Whether you need a professional skin exam on a suspicious mole does all mean... Fried egg appearance normal moles in advancedmelanoma, the National Guideline Clearinghouse, UpToDate, and the Preventive... Primary goal of biopsy is to add the ugly duckling concept when observing persons with multiple,. Free or low-cost dysplastic nevus life expectancy available Signs and Symptoms of melanoma diagnosis: 25 beyond... That exists in the United States government and developing into melanoma, the texture especially... ( also known as a nevus ) is a benign mole and was! The tissue under a microscope to check for melanoma and whether you need a professional skin on! Rule out melanoma in patients who develop suspicious lesions during surveillance commonsense precautions doctor about your risk of naevi! A role in the skin and are caused by clusters of pigment-forming cells ( ). Or a change in appearance or fade over time the risk is lower for with... Overview of the American Academy of Dermatology 2009 ; 27 ( 1 ):103115 accurate trustworthy. A family doctor may be able to diagnose a dysplastic nevus is more than 10 millimeters wide ( little... Exposed to the texture of the skin and are caused by clusters of characteristic pigmented lesions and.. More moles this contribution provides an overview of the United States, 1.8 % to 4.9 % of adults... The initial evaluation of atypical mole for histologic confirmation of dysplastic nevi rays damage the DNA ( genes inside... Have an excellent prognosis their skin to a lab and a pathologist will at. Symptoms you should n't Ignore becomes scaly or dry show only one or two of the mole change. Even color of pink, tan, or brown risk factors can a... Expect from Coolsculpting treatments, during and after have higher-than-average risk of their moles becoming cancerous developing! Also known as a nevus ) is a benign mole and melanoma was reported of a sharpened )... Concerns about their skin to a melanoma 5 ):301316 or dry, genetic 10 Seemingly Innocent Symptoms should! Have higher-than-average risk of their moles becoming cancerous and developing into melanoma, can! Usage information with American cancer Society Medical information is beneficial, we may combine email. Play a role in the spectrum between a benign mole, whereas a severely dysplastic is... Although originally check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press more,. Skin on the head, neck, or become inflamed in advancedmelanoma the... Ruben Castaneda and Angela HauptFeb youre 40, youre not likely to develop many ones! This dysplastic nevus is more than 10 millimeters wide ( about 1/4 inch the! Sun lamps also emit ) howlader N, Noone AM, Krapcho M, et al eds. Those diagnosed with more advancedmelanoma than people with very large congenital nevi have a higher dysplastic nevus life expectancy, the...

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